1) Every morning, he leaped out of bed, eager to seize the day with an 'up
and at them' attitude.
2) She woke up early, feeling
refreshed and ready to tackle the day's challenges with a determined 'up
and at them' attitude.
Etymology
The phrase is a colloquial expression that
likely originated as an enthusiastic encouragement to get out of bed and
start the day with energy and determination.