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Iodine Deficiency and Its Global Toll on Intelligence
 
In an era of fervent debate surrounding the nature of intelligence, it may be startling to discover that within China alone, an astounding 480 million IQ points have been lost—due to nothing more than a simple chemical deficiency. This shortfall, however, could be resolved at the minimal cost of just a few cents per person annually.

Globally, more than 20 million people have been denied their full intellectual potential simply because they lacked access to a crucial nutrient. This deficiency threatens around 1.6 billion individuals, comprising nearly a quarter of the world's population. In some nations, the absence of this chemical has led to an alarming drop in average IQ scores, causing a downward shift of 13 points in the intelligence distribution curve.

The missing ingredient is iodine, element number fifty-three on the periodic table. Though it has largely been eradicated from the diets of affluent societies, iodine deficiency remains the root cause of what might be the most overlooked epidemic in human history.

Micronutrients, like iodine, are essential in minuscule amounts for sustaining human health. A person needs only one ten-thousandth of a gram of iodine daily—amounting to a mere two grams over a lifetime.

A global initiative is now underway to eliminate iodine-deficiency disorders by the end of this decade, primarily through the iodization of salt. While other methods of supplementation exist, salt remains the cheapest and most accessible option.

Iodine deficiency is the leading cause of cognitive impairment worldwide. It can result in severe consequences such as mental retardation, deaf-mutism, and partial paralysis, but it also manifests in subtler ways: clumsiness, lethargy, and diminished learning capacity.

The role of iodine is fundamental in the production of thyroid hormone, which is essential for brain development during fetal life and later regulates metabolism. When iodine is insufficient, the body cannot produce adequate levels of thyroid hormone.

This hormone is produced in the thyroid gland, which wraps around the front of the neck. If the hormone supply dwindles, the thyroid gland enlarges, forming a condition known as goiter. In extreme cases, goiters can reach grotesque sizes. Although other factors, such as hormonal imbalances, can contribute to goiter, iodine deficiency is by far the most common cause.

In lower vertebrates, the thyroid hormone controls dramatic changes, such as a tadpole's metamorphosis into a frog or the migration of a young flounder's eyes to one side of its head. In humans, the hormone’s developmental responsibilities are primarily focused on the brain.

Severe iodine deficiency during pregnancy can result in cretinism—a permanent disability marked by profound mental retardation, deaf-mutism, muscle stiffness, and often stunted growth.

However, research shows that providing iodine supplements to pregnant women before the second trimester can entirely prevent cretinism. Even if supplementation is introduced later in pregnancy or in early childhood, it can significantly reduce neurological damage, although it cannot reverse it fully.

Numerous studies have demonstrated that even mild iodine supplementation can improve cognitive function in those with a deficiency. In one notable study conducted in Malawi, where up to 86% of children in certain villages were mildly iodine deficient, schoolchildren who received iodine supplements showed remarkable improvements in verbal fluency, visual memory, and eye-hand coordination. Although their IQ was not directly measured, researchers estimated an average increase of 21 points.

Yet, iodine is no miracle cure for intelligence. Supplementation benefits only those with a deficiency; excess iodine can be harmful and does not enhance brain function in individuals who are not deficient.

This overlooked epidemic can be solved, yet it continues to hinder millions from reaching their full intellectual potential. The solution is simple, the cost is minimal, but the impact is profound.
 
 
 

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